JZL184, IUPAC name 4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylate, was a small-molecule chemical compound that was a specific inhibitor of monoacylglycerol lipase (MAGL), with near-complete inhibition at approximately 1.0 nM.
Behind the ScenesEdit
- In the real world, JZL184 was synthesized and characterized by Long et al. in 2009 at the Scripps Research Interest at California, United States of America.
- Article writer RelentlessRecusant found out about JZL184 through his personal studies in chemical biology.
- ↑ Long et. al (2009). Selective blockade of 2-arachidonoylglycerol hydrolysis produced cannabinoid behavioral effects. Nature Chemical Biology (5): 37-44.