Bene Gesserit Sisterhood

The Bene Gesserit Sisterhood were an all-female, all-human order of Force users who were geneticalle engineered to use the Force to boost their intelligence to thousands of times the human norm. They functioned like hyper-intelligent computers, and were sometimes called Mentats.

Part of the reason for the Bene Gesserit order was the bias within the Milky Way Imperium against computers and droids with artificial intelligence.